Clinical trials and tribulations: the MASCOT study.

Medicare's coverage with study participation policy: clinical trials or tribulations?

Lessons to be learnt from unsuccessful clinical trials.

In Thorax, Lenney and colleagues have described their trials and tribulations with the MASCOT study, which compared three different treatment options in children with asthma whose condition was not adequately controlled on low-dose inhaled corticosteroids (ICS). The study, which aimed to initially recruit 900 children and enter 450 into a randomised comparison, recently had to close because it ...

Neurokinin-1 receptor antagonists as novel antidepressants: trials and tribulations.

Based upon animal experiments and early clinical trials, neurokinin-1 receptor antagonists showed promise as novel antidepressants. Subsequently, however, more extensive clinical trials did not reveal evidence of efficacy in depression. The development of novel antidepressants will require a better understanding of the neural basis of antidepressant action in humans.

The Trials and Tribulations of CETP Inhibitors

The Trials and Tribulations of Cross - Cultural Research

In press Trials and Tribulations, 2 The Trials and Tribulations of Cross-Cultural Research Those of us who do cross-cultural research usually have a story of precisely when we began our journey into the global territory of research. For some, the interest might have developed at a very young age; for others it might have been happenstance, having stumbled into the field after doing work within ...